HOW IT WORKS
HOW KESIMPTA WORKS
KESIMPTA is the only B-cell treatment for RMS that’s delivered as a once-monthly* at-home auto-injection.
*Once monthly after 3 weekly starter doses.
WHAT HAPPENS IN RMS
To understand how KESIMPTA works, it’s important to know how B-cells and relapsing MS are connected.
For illustrative purposes only.
 | B-cells B-cells are part of the immune system that helps fight infections. They are found throughout the body. |
 | RMS-related B-cells In RMS, immune cells, such as B-cells, located in the lymph nodes, are mistakenly sent to attack the body's myelin—the protective covering around the nerves in the brain and spinal cord. |
KESIMPTA IS PRECISELY DELIVERED
While it is not fully understood how KESIMPTA works, it is designed to target the B-cells† in the lymph nodes believed to play a role in RMS.
Think of your body like a maze:
For illustrative purposes only.
| RMS-related B-cells As a subcutaneous injection just under the skin, KESIMPTA is thought to target a precise path to RMS-related B-cells in the lymph nodes.† |
 | B-cells The targeted delivery is thought to limit the impact on other B-cells your body needs to maintain immune function. |
†Based on preclinical studies.
ANDY M.
Dad, Account Executive, and Real Patient
Chose KESIMPTA as 1st treatment: 2022
“Learning more about B-cell treatments and how KESIMPTA was precisely delivered made me feel more comfortable getting started.”
Up Next:
Check out the proven safety profile of KESIMPTA.
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Want co-pay help?
96% of all prescriptions filled paid as little as $0 out of pocket cost when used with the Co-Pay Plus offer.‡§
All people featured on this webpage are living with relapsing multiple sclerosis, have taken KESIMPTA, and have been compensated for their time.
RMS, relapsing multiple sclerosis.
‡Limitations apply. Valid only for those with private insurance. The Program includes the Co-Pay Plus offer, Plus Card (if applicable), and Rebate, with a combined annual limit up to $18,000. Patient is responsible for any costs once limit is reached in a calendar year. Program not valid (i) under Medicare, Medicaid, TRICARE, VA, DoD, or any other federal or state health care program, (ii) where patient is not using insurance coverage at all, (iii) where the patient’s insurance plan reimburses for the entire cost of the drug, or (iv) where product is not covered by patient’s insurance. The value of this program is exclusively for the benefit of patients and is intended to be credited towards patient out-of-pocket obligations and maximums, including applicable co-payments, coinsurance, and deductibles. Program is not valid where prohibited by law. Patient may not seek reimbursement for the value received from this program from other parties, including any health insurance program or plan, flexible spending account, or health care savings account. Patient is responsible for complying with any applicable limitations and requirements of their health plan related to the use of the Program. Valid only in the United States and Puerto Rico. This Program is not health insurance. Program may not be combined with any third-party rebate, coupon, or offer. Proof of purchase may be required. Novartis reserves the right to rescind, revoke, or amend the Program and discontinue support at any time without notice. See complete Terms & Conditions at start.kesimpta.com.
§2025 data on file.